For the final game of Week 11, the San Francisco 49ers (5-4) head to the desert, where they face a divisional matchup against the Arizona Cardinals (4-6) at State Farm Stadium. Both teams are trying to keep pace with the Seattle Seahawks, who are at the top of the division with a 6-4 record. A San Francisco win would move the Niners into first place by way of their head-to-head win over the Seahawks earlier in the season. The Cardinals are trying to dig their way out of an early season hole and build on the momentum of last week’s 27-17 win over the defending Super Bowl Champion Los Angeles Rams.
How to Watch San Francisco 49ers at Arizona Cardinals Today:
Game Date: Nov. 21, 2022
Game Time: 8:15 p.m. ET
TV Channel: ESPN
Live stream the San Francisco 49ers at Arizona Cardinals game on fuboTV: Start with a free trial!
The Niners are coming off a win as well, having beaten the Los Angeles Chargers 22-16 last week. It was a big game for the San Francisco pass rush, which recorded three sacks.
This will be the first matchup between the Niners and Cardinals this year. Last year, the Cards swept San Francisco and have won 11 of the last 14 head-to-head meetings.
Regional restrictions may apply.